62 research outputs found

    A Roadmap for UEML

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    International audienceA Roadmap for Unified enterprise modelling languag

    Analyse comparative de méthodologies et d'outils de construction automatique d'ontologies à partir de ressources textuelles

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    International audienceOver the recent years, several methodologies and tools for the automatic construction of ontologies from textual resources have been proposed. In this article we first analyze four of these approaches by comparing them with a reference approach - Methontology. We choose approaches which cover all the steps of the ontology construction process. Then, for some tools associated with the previously analyzed approaches, we analyze their performances and compare their results with manually obtained results

    Analyse comparative de méthodologies et d'outils de construction automatique d'ontologies à partir de ressources textuelles

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    International audienceOver the recent years, several methodologies and tools for the automatic construction of ontologies from textual resources have been proposed. In this article we first analyze four of these approaches by comparing them with a reference approach - Methontology. We choose approaches which cover all the steps of the ontology construction process. Then, for some tools associated with the previously analyzed approaches, we analyze their performances and compare their results with manually obtained results

    Gluten sensitivity and neurological manifestations

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    The authors report on six cases of gluten-sensitivity, also defined non-celiac gluten sensitivity, characterized by abdominal features (diarrhea, bloating, pain), genetic positivity for predisposition to celiac disease (DQB1* 02 in all cases; DQA1*05 in three; DQA1*02 in two, DQB1*03 in two), negative anti-t-Transglutaminase antibodies, normal mucosa on biopsy in four cases, type 1 of Marsh in one case. The subjects presented frequent central nervous system (CNS) symptoms: headache in three patients, somnolence in one, electroencephalogram aspecific alterations in three (in two of them with previous seizures), leptomeningeal cyst in one, intracranial calcification in one, cerebral gliosis in two. After a gluten-free diet, all intestinal and clinical CNS features remitted, but re-appeared after gluten reintroduction. On the basis of the neurological signs, the authors stress the relevance of immune innate system in the pathogenesis of these cases with possible subsequent evolution on immune adaptive system involvement

    Oculo-auriculo-vertebral spectrum with myopathy and velopharyngeal insufficiency. A case report with a non-branchiomeric muscle biopsy

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    In the present paper we report on a case of oculo-auriculo-vertebral spectrum presenting fluorescence in situ hybridization and comparative genomic hybridization tests negative, hypotonia of some branchiomeric muscles (with velo-pharyngeal insufficiency, dysphagia and nasal voice) and non-branchiomeric muscles (with strabismus and limb hypotrophy). On the basis of the left quadriceps muscle biopsy, showing anisometry and prevalence of type 1 fibers, and on literature data, we underline the relevance of TBX1 gene (regulator of neural crest cells and activator of myogenic factors in branchiomeric muscles development) and of PAX3 gene (present in neural crest, inducing migration of these cells and reported in non-branchiomeric muscles). We conclude that the case of OAVS presented a generalized myopathy and we hypothesize that a cluster of genes strictly neural crest cells related, including TBX1 and PAX3, may be responsible of the branchiomeric and non-branchiomeric myopathy; alternatively, a regulatory mechanism abnormally common to OAVS and velo-cardio-facial syndrome could be present

    Oculo-auriculo-vertebral spectrum with craniosynostosis and osteo-cartilagineous multiple defects: a diffuse chondro-membranous-osteo-dysplasia.

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    We report on a female with oculo-auriculo-vertebral spectrum, low height, and on X-ray lambdoid suture synostosis, cerebral cyst/mild holoprosencephalia and cholesteatoma, and multiple abnormalities of bones of chondral origin. On the right side, maxillary, mandibular bones, external auditory canal, middle ear were hypoplastic as well as semicircular canal, cranial base, bones vestibule. On the left side, coclea, timpanic cavity, mastoid antrum were hypoplastic, while stapes was misshapen. Limbs bones were slender with thin metaphyses and some carpal bones were absent. Hand second phalanx was hypoplastic and fifth finger presented clynodactily. Lambdoid synostosis expressed membranous ossification abnormality. We hypothesize that during the blastogenesis a mutation of a factor responsible for abnormal generalized endochondral and connectival ossification (possibly fibroblast growth factor receptor) occurs

    The M*-object methodology for information system design in CIM environments : the conceptual design phase

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    M*-OBJECT is a methodology for the analysis, design and implementation of CIM information systems. In this paper, the conceptual design phase is presented. It starts from users information requirements and provides a conceptual specification, the conceptual schema, of the information system to be used in the integrated manufacturing system to be designed. This methodological phase is supported by the Process and Data Net (PDN) model which integrates an objet-oriented data model, a query and data manipulation language, a process model, and an object behaviour description model. The major features of the specification approach are : static, dynamic, and behavioural properties of information are fully covered, complex data structures and data manipulation can be specified, and specifications are executable for rapid prototyping

    The Unified Enterprise Modelling Language – Overview and further work

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    International audienceThe Unified Enterprise Modelling Language (UEML) aims at supporting integrated use of enterprise and IS models expressed using different languages. To achieve this aim, UEML offers a hub through which modelling languages can be connected, thereby paving the way for also connecting the models expressed in those languages. This paper motivates and presents the most central parts of the UEML approach: a structured path to describing enterprise and IS modelling constructs; a common ontology to interrelate construct descriptions at the semantic level; a correspondence analysis approach to estimate semantic construct similarity; a quality framework to aid selection of languages; a meta-meta model to integrate the different parts of the approach; and a set of tools to aid its use and evolution. The paper also discusses the benefits of UEML and points to paths for further work

    The unified enterprise modelling language – Overview and further Work

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    ISBN 978-1-1234-7890-2/08International audienceThe Unified Enterprise Modelling Language (UEML) aims to support integrated use of enterprise and IS models expressed in a variety of languages. The achieve this aim, UEML provides a hub through which different languages can be connected, thereby paving the way for connecting the models expressed in those languages. UEML offers a structured approach to describing enterprise and IS modelling constructs, a common ontology to interrelate construct descriptions at the semantic level, a correspondence analysis approach to estimate semantic construct similarity, a quality framework to aid selection of languages, a meta-meta model to organise the UEML and a set of tools to aid its use. This paper presents an overview of UEML and points to paths for further work

    A Unified Enterprise Modelling Language for enhanced interoperability of Enterprise Models

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    International audienceThere is a serious backwardness in awareness, acceptance and wide use of the Enterprise Modelling (EM) technology in industry because enterprises cannot capitalise from previous modelling efforts. This situation hinders true enterprise integration, interoperability, and enterprise knowledge sharing. A Unified Enterprise Modelling Language, based on meta-modelling of existing EM Languages, would serve as an Interlingua between EM tools providing the business community with a common visual, template based language to be used on top of most commercial enterprise modelling and workflow software tools
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